Ikigai and Mortality

Objective: To investigate the association between the sense of “life worth living (ikigai)” and the cause specific mortality risk. The psychological factors play important roles in morbidity and mortality risks. However, the association between the negative psychological factors and the risk of mortality is inconclusive. Methods: The Ohsaki Study, a prospective cohort study, was initiated on 43,391 Japanese adults. To assess if the subjects found a sense of ikigai, they were asked the questio...

 Ikigai and Mortality

Among the 43,391 subjects enrolled, 25,596 (59.0%) indicated that they found a sense of ikigai, 15,782 (36.4%) indicated they were uncertain, and 2013 (4.6%) indicated they did not find a sense of ikigai. As compared with those who found a sense of ikigai, those who did not were more likely to be unmarried, unemployed, have a lower educational level, have bad or poor self-rated health, have a high level of perceived mental stress, have severe or moderate bodily pain, have limitation of physic...

 Physical and Actuarial Escape Velocities

The escape velocity cusp is closer than you might guess. Since we are already so long lived, even a 30% increase in healthy life span will give the first beneficiaries of rejuvenation therapies another 20 years—an eternity in science—to benefit from second-generation therapies that would give another 30%, and so on ad infinitum. Thus, if first-generation rejuvenation therapies were universally available and this progress in developing rejuvenation therapy could be indefinitely maintained, the...

 Correlation != Causation; However, It is Often All We Have

> correlation doesn't mean causation. As a statistician, I guess I should be happy that more people are aware of this. But I also think too many people are taking "correlation != causation" superficially. I mean, almost all of science is based on significant correlational findings, especially when the traditional way to prove causation (i.e. via randomized trial) is unethical (i.e. we can't randomly assign people to be insured vs. uninsured). Along these lines, I often find people who sa...

 Gompertz Law of human mortality

What do you think are the odds that you will die during the next year? Try to put a number to it — 1 in 100? 1 in 10,000? Whatever it is, it will be twice as large 8 years from now. This startling fact was first noticed by the British actuary Benjamin Gompertz in 1825 and is now called the “Gompertz Law of human mortality.” Your probability of dying during a given year doubles every 8 years. For me, a 25-year-old American, the probability of dying during the next year is a fairly minusc...